I've always been impressed with Cincinnati's riverfront. The downtown skyline has an interesting mix of old stone buildings and newer progressive architecture. It is not too unlike Minneapolis, but with a milder climate.
Cincinnati is known as the Queen City and the Gateway to the South. The many bridges that span the Ohio River offer good views of the downtown skyline and Northern Kentucky area. There are walkways on many of them so it's not hard to get a good photo or make your way by foot to attractions in Northern Kentucky.
If you going for a walk along the Ohio River be sure to check out the Purple People Bridge, the historic Roebling Suspension Bridge (Think of the movie "Rainman") and the Big Mac bridge - it's the one that looks like a golden arch.
One has many choices as a visitor to Cincinnati. Yes, there's two famous versions of Chili - Gold Star or Skyline Chili. And it's not just the choices with food, it's what to do. There's Fountain Square downtown, riverboat cruises along the Ohio River, and if you still haven't seen enough water, consider a stop at the Newport Aquarium - it has a "Million Gallons of Fun". At least that's what its web site promises.
Cincinnati has great museums, a world class zoo and the Kings Island Amusement Park is a short drive north. The Queen City is a great place to take in a ballgame as ticket prices, hotels and parking are cheaper than many big-city venues.
Cincinnati has two newer sports facilities set along the Ohio River. The Reds play at Great American Ballpark and the Bengals at Paul Brown stadium. If you're going to a Reds game, you can bring you own food in. Paul Brown Stadium is the only football stadium to make a list of "America's favorite 150 buildings and structures," according to a Harris Interactive survey.
If you have business at the University of Cincinnati, the best place to stay is the Marriott Kingsgate. It's also close to the Cincinnati Zoo.